Insulin-producing beta cell replication sustained for four+ weeks

There has been some pretty exciting new developments in the world of diabetes care.  Not suggestions from the ADA of course, they are busy telling us all to eat high carbohydrate diets in the face of all logic (more on this soapbox another day…).  But in the realm of science, it is really starting to look promising.  This new research from the University of Pittsburgh School of Medicine in Diabetes, (which is indeed) a journal of the American Diabetes Association.

They also found several cocktails of molecules that drive human beta cells to replicate, as well as important differences between mouse and human beta cells that could influence how these approaches are best used to treat diabetes, which is caused by insufficient insulin production leading to abnormal blood sugar levels.

“Our team was the first to show that adult human beta cells can be induced to proliferate or grow at substantial rates, which no one thought possible before,” said senior author Andrew F. Stewart, M.D., professor of medicine and chief of the Division of Endocrinology and Metabolism, Pitt School of Medicine. “Now our effort has been to unravel these regulatory pathways to find the most effective strategy that will allow us to treat — and perhaps cure — diabetes by making new insulin-producing cells.”

Science Daily

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